http://campar.in.tum.de/Students/DaSimDem

MA/DA: Simultaneous Deformation of Medical Images

Brain Image

26.05.2009, Diplomarbeiten, Bachelor- und Masterarbeiten

The registration – spatial alignment – of images is of great interest for medical image processing and general computer vision tasks. Often, not just the registration of two images, but the registration of multiple images is needed. An example is the creation of a medical brain atlas, for which a number of brain volumes have to be aligned. Since the human brains vary significantly, a deformable registration or warping between the images is necessary to correctly align the images. In the scope of this thesis, we will implement an algorithm for simultaneous deformable registration. http://campar.in.tum.de/Students/DaSimDem

An example for 40 brain images before registration are shown on the right (courtesy of L. Zöllei). The registration of the images is necessary for the atlas construction, which basically corresponds to the calculation of the mean of a population of images. On the atlas image on the lower right, the mean before and after the alignment is shown. One can clearly see the improvement and clarity of structures after the alignment.

In the scope of this master or diploma thesis we want to implement a simultaneous deformable registration algorithm. For this purpose, the open source registration toolkit (ITK) will be used, which already provides a huge set of functionalities. This project is matter of current research and of high interest for the research community.

The student should have experience working with C++ and image processing. Moreover, basic mathematical skills are necessary for understanding the underlying theory.

Kontakt: Christian Wachinger, wachinge@in.tum.de, http://wwwnavab.in.tum.de/Main/ChristianWachinger

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